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From discovery to impact: How Glyco Diagnostics aims to change the fight against liver fibrosis

Glyco Diagnostics is developing an innovative liver fibrosis test to help diabetes patients detect liver problems early. Katarina Madunic and her team are committed to enabling doctors and patients to take action in time, before any damage becomes irreversible.

The story of Glyco Diagnostics began at Leiden University Medical Center. There, co-founder Manfred Wuhrer and his team discovered a promising biomarker in the blood of patients with liver fibrosis. They found it in glycan molecules, which are small sugar molecules attached to proteins in our blood, produced by the liver

Moving back to Leiden for her startup

“Every researcher dreams that one day their work will really mean something to society,” Katarina says. For her, that dream took shape when she decided to return from her postdoc in Copenhagen. She took on the challenge of bringing their biomarker to the clinic by starting her own company in Leiden.

Before she took that step, Katarina first followed PLNT‘s Ready to Start program. All the way from Copenhagen, completely online. “That was my first introduction to entrepreneurship and the world of startups. It showed me how exciting and challenging it is to really get an idea off the ground.”

With unlock_ from idea to startup

unlock_ proved to be the perfect springboard to grow from an idea to a real business. “I had zero experience with entrepreneurship or finance,” Katarina laughs.

Every Tuesday, together with Manfred and the other participants of unlock_, she learned everything involved in building a startup: strategy, pitching, investors, regulations. She found the latter in particular boring at first. “I always found rules and documents annoying, but now I understand why they are there. In the end, everything is about patient safety and that motivates.”

“Everything was new to me, but because of that I learned an awful lot in a short period of time.”

According to Katarina, the real power of unlock_ is in the people. Mentors like Christian and Sven were always available, even outside of classes. “We didn’t just get theory. We built our business in practice. Even during lunch, people helped us with our pitch or business plan.” The fortnightly sessions with Stefan Ellenbroek also provided valuable insights on how to bring academic breakthroughs to the clinic.

Growing together with unlock_ community

The biggest challenge? “We really had to start from scratch. No pitch, no presentation, not even a clear business model. That was tough, but also an opportunity to learn quickly.” Katarina discovered that she gets the most energy from writing inspiring research proposals and discussing clinical data with others. Fortunately, Manfred complements her with his financial background.

For Katarina, unlock_ felt like a community where everyone helped each other get ahead. “We help each other with things like LinkedIn, marketing and financing. Everyone has their own expertise. You realize you’re not alone.”

De komende maanden richten ze zich op grote stappen: het verkrijgen van een IP-licentie van het LUMC, het officieel oprichten van hun bedrijf en het indienen van nieuwe subsidieaanvragen. De grote droom is dat over vijf jaar iedere huisarts hun test gebruikt om diabetespatiënten te screenen. Zo kan leverfibrose eindelijk vroeg worden ontdekt en behandeld. Katarina is duidelijk:

“We really want to make a difference and prevent people from getting sick unnecessarily.”

When asked to describe unlock_ in one word, she does not hesitate for a moment: “community.” Her advice to other founders: “Keep asking questions and use the knowledge and experience in the network. Together you will get much further than alone.”

Bekijk ook deze succesverhalen

Bij Venture Academy hadden we echt wat aan elkaar. Je leert enorm veel van de ervaringen van andere teams.

Laura Mezzanotte

Co-Founder Radigene
Het [Get Things Done Day] doet me een beetje denken aan een hackathon of studeren in de bibliotheek voor je tentamens. Iedereen is gefocust bezig, en het is gewoon fijn om het gevoel te hebben dat je ergens bij hoort.

Sekou Donzo

Founder Spectral Sounds
Als je serieus bent en je afspraken nakomt, maakt het mensen echt niet uit welk niveau je hebt gedaan.

Sam van Braam

Student ondernemen en handel MBO Rijnland
“Een startup bouwen naast je studie is soms puzzelen met je tijd, maar als je er echt in gelooft, maak je er ruimte voor.”

Jelke en Sophia

Co-founders Luisterlijk
“De coaches en andere startups zijn altijd bereid om te helpen en je met de juiste mensen te verbinden. Ze pushen je, maar op een positieve manier.”

Milad Mohammadi

Co-founder PrepareConsult
De combinatie van coaching, een sterke peergroep en lessen van ervaren ondernemers heeft me enorm geholpen.

Florian schimmel

Founder Opal
“Hoe eerder je begint, hoe groter je kansen,” 

Robert Krams

Founder CureLogic
For me, it was essential to better understand the healthcare system. unlock_ put me in touch with experts from biotech, health law and medical technology.

Darshan Ramanagoudra

Founder MyClusters
Just do it [startup startup]. Don’t hesitate, because the worst that can happen is that you learn a tremendous amount.”

Jolke Beijnvoort

Co-founder VINDI Biosystems
Dankzij unlock_ heb ik waardevolle samenwerkingen opgezet.

Alicia Valenzuela

Founder Pulmonavat
unlock_ heeft me geleerd dat je zonder netwerk nergens komt.

Dmitry Pavlotsky

Co-Founder GameAnalyze
Ik wilde deel uitmaken van het Leidse ecosysteem en de connectie voelen tussen de plek waar ik woon en de plek waar ik werk, dat doe ik nu zeker.

Joris Castermans

CEO van Whispp
Het kan hier [PLNT] soms chaotisch zijn, maar de chaos is geweldig; de interactie met andere mensen is wat ons stimuleert.

Ken Ramroochsingh

CEO van Smartnotation
Mijn grootste tip is om te mengen met andere studenten die geïnteresseerd zijn in ondernemerschap. De inspiratie, steun en kansen die je uit zo’n omgeving haalt, zijn echt ongekend. Ik kan dan ook iedereen aanraden om bij PLNT langs te gaan!

Serafine

Founder Elementary the Game
[At PLNT] we have many qualified students, the infrastructure of laboratories and other pharmaceutical companies nearby.

Niall

Founder SeraNovo
Alles wat we vandaag hebben, is 100% te danken aan ons netwerk, en PLNT heeft ons echt geholpen om dat te bieden.

Violette Defourt

CEO Rapidemic
It is very different if you can experience the information instead of just reading it.

Robin de Lange

Founder Virtual Reality Lab
Why focus on trading pictures instead of solutions?

Jeroen van Gessel

Founder of EduFace
We both love gaming, and over a beer we figured we wanted to play a game related to the study, in which immune systems battle infectious diseases.

Rafael Jezior en Dennis de Beeld

Co-founders Immunowars
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