{"id":5517,"date":"2022-02-18T14:59:00","date_gmt":"2022-02-18T13:59:00","guid":{"rendered":"https:\/\/plnt.nl\/?post_type=nieuwsberichten&#038;p=5517"},"modified":"2024-01-19T16:56:57","modified_gmt":"2024-01-19T15:56:57","slug":"e350-000-voor-startup-exit071-vanuit-uniiq-en-leh","status":"publish","type":"nieuwsberichten","link":"https:\/\/plnt.nl\/en\/news\/e350-000-voor-startup-exit071-vanuit-uniiq-en-leh\/","title":{"rendered":"\u20ac350.000 voor startup EXIT071 vanuit UNIIQ en LEH"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5517\" class=\"elementor elementor-5517\" data-elementor-post-type=\"nieuwsberichten\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4db654e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4db654e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7690954\" data-id=\"7690954\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bb96992 elementor-widget elementor-widget-text-editor\" data-id=\"bb96992\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Leiden, 15 februari 2022 &#8211; Proof-of-conceptfonds\u00a0<a href=\"https:\/\/uniiq.nl\/\" target=\"_blank\" rel=\"noopener\">UNIIQ<\/a>\u00a0investeert met\u00a0<a href=\"https:\/\/www.universiteitleiden.nl\/en\/about-us\/management-and-organisation\/libertatis-ergo-holding-bv\" target=\"_blank\" rel=\"noopener\">LEH<\/a>\u00a0(Libertatis Ergo Holding) in totaal \u20ac 350.000 in de Leidse startup\u00a0<a href=\"https:\/\/exit071.com\/\" target=\"_blank\" rel=\"noopener\">EXIT071<\/a>. EXIT071 ontwikkelt een nieuwe techniek voor de analyse van exosomen. Exosomen zijn kleine deeltjes (extracellar vesicles) in o.a. bloed die specifieke informatie bevatten over hun plek van herkomst (bijvoorbeeld brein, lever, etc.). Deze informatie zou een grote rol kunnen spelen in diagnostiek, maar momenteel is het technisch nog heel moeilijk om vanuit complexe biologische samples exosomen te isoleren en karakteriseren. Met hun gepatenteerde microflu\u00efdische chip kan EXIT071 exosomen analyseren op een snelle, reproduceerbare manier, voor diagnostische en therapeutische toepassingen. De investering zal gebruikt worden voor het finetunen van de chip, de ontwikkeling van een systeem dat het analyseproces automatiseert, teamuitbreiding en versterking van de IP-positie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-bf1941c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"bf1941c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5881aab\" data-id=\"5881aab\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c0fcefe elementor-widget elementor-widget-text-editor\" data-id=\"c0fcefe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Toepassingen van exosomen zijn veelbelovend<\/h3><p>EXIT071 is een vroege-fasestartup die zich bezighoudt met de ontwikkeling van innovatieve technologie voor de analyse van exosomen. Exosomen zijn relatief nieuw in het veld van diagnostiek en therapie, maar hebben veel potentie. Het zijn deeltjes van nanoformaat die door alle cellen gemaakt worden om onderling boodschappen uit te wisselen. Ze geven een momentopname van gezondheids- of ziektetoestand van organen en zijn aanwezig in alle lichaamsvloeistoffen (bloed, urine, cerebrospinale vloeistof, tranen, etc.). Daarmee bieden ze enorme potentie voor niet-invasieve, vloeibare biopsiediagnostiek voor onder andere oncologie, longziekten, neurodegeneratieve ziekten en prenatale diagnostiek. Door exosomen in zulke biopsie\u00ebn te analyseren kunnen ziektes aan het licht komen door veranderingen in de hoeveelheid exosomen en de moleculaire inhoud (eiwitten, miRNAs, metabolieten) van zieke cellen te vergelijken met die van gezonde cellen. Naast hun diagnostisch potentieel is recentelijk ook het therapeutisch potentieel van exosomen erkend, onder andere door investeringen van \u20ac2 mrd., alleen al in 2020, door farmaceutische bedrijven en Venture-Capitalpartijen.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2e2c3e5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2e2c3e5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9b1ee6e\" data-id=\"9b1ee6e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8fd41e7 elementor-widget elementor-widget-image\" data-id=\"8fd41e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"367\" src=\"https:\/\/plnt.nl\/wp-content\/uploads\/2023\/02\/EXIT071.jpg\" class=\"attachment-large size-large wp-image-5520\" alt=\"\" srcset=\"https:\/\/plnt.nl\/wp-content\/uploads\/2023\/02\/EXIT071.jpg 980w, https:\/\/plnt.nl\/wp-content\/uploads\/2023\/02\/EXIT071-300x138.jpg 300w, https:\/\/plnt.nl\/wp-content\/uploads\/2023\/02\/EXIT071-768x353.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-afbc17d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"afbc17d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e880b79\" data-id=\"e880b79\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-845cb47 elementor-widget elementor-widget-text-editor\" data-id=\"845cb47\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Innovatieve technologie<\/h3><p>Huidige methoden presteren onvoldoende en zijn omslachtig. Met de microflu\u00efdische chip van EXIT071 is het mogelijk om exosomen te scheiden met een hogere zuiverheid en opbrengst. Daarnaast is de chip geschikt om in een high-throughput-opstelling gebruikt te worden. De originele technologie, depletion zone isotachophoresis, is uitgevonden en gepatenteerd aan de Universiteit Leiden door Prof. Thomas Hankemeier, Hoofd van de Analytical BioSciences and Metabolomics groep en medeoprichter van MIMETAS. EXIT071 heeft onlangs een exclusieve licentieovereenkomst getekend en is van plan om hun deep-tech-innovatie naar de therapeutische en diagnostische exosoomindustrie te brengen.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a060ddc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a060ddc\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-21bbb00\" data-id=\"21bbb00\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-86db51b elementor-widget elementor-widget-text-editor\" data-id=\"86db51b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Nanotechnologie als sleutel van de innovatie<\/h3><p>De nanoformaat structuren zijn een belangrijk onderdeel van de werking van de microflu\u00efdische chips en ze zijn zeer uitdagend om te produceren. Daarom werkte EXIT071 samen met SINTEF MiNaLab in Noorwegen, een professionele leverancier van nanotechnologie, om constante en hoge kwaliteit te garanderen. Het productieproces van de chip is ontwikkeld binnen academische samenwerking in een EuroNanoMEd 3 Project, EXIT (EXosomes Isolation Tool.) De startup wordt geleid door oprichter en CEO Dr. Yuliya Shakalisava, expert in microflu\u00efdische technologie. De technologie wordt verder ontwikkeld in samenwerking met Universiteit Leiden met advies van Prof. Thomas Hankemeier.<\/p><p>De investering zal gebruikt worden voor het finetunen van de chip, de ontwikkeling van een systeem dat het analyseproces automatiseert, teamuitbreiding en versterking van de IP-positie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4ad4c63 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4ad4c63\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d517aa3\" data-id=\"d517aa3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8e6d2f4 elementor-widget elementor-widget-button\" data-id=\"8e6d2f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Meer van UNIIQ<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":5712,"template":"","class_list":["post-5517","nieuwsberichten","type-nieuwsberichten","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - 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